Chapter 1850 Studying Vascular Calcification? Grand Duke, Don’t Eat Blood Vessels! (Ask for Monthly Ticket)

(ScarletC will be rewarded with more rewards)

Gretel signed a magic agreement with Earl Sutherland, so he doesn't need to worry about the rest. He happily ran back to his mage tower and slapped the papers and agreements on the table:

"Mr. Norwood——"

"Sir, what's the matter?"

"Mr. Norwood, I have secured investment, and the subsequent negotiations with the Alchemy Guild will depend on you!"

He tricked the pharmacists of the Alchemy Guild into working as coolies to study how to artificially extract oxytocin;

Negotiate an agreement with the Alchemy Guild. After the oxytocin is artificially extracted, Oak Forest Hospital will purchase how much and what the purchase price will be;

How much is the external sales, how much is Oak Grove Hospital's share during the external sales process, and how much is Earl's Palace's share;

Including controlling the research plans of pharmacists and supervising them not to spend research funds indiscriminately. Of course, these tasks are done by Mr. Norwood, a fifteenth-level transformation master, a famous alchemist, and the inventor of various rubber products!

The boss left the shop, and Mr. Norwood had no choice but to read through the paper and engage in business negotiations diligently. And Gretel himself, no doubt, happily plunged into basic research:

"Your Majesty the Grand Duke, regarding the problems of fat accumulation, blood vessel narrowing, and arteriosclerosis in blood vessels, how is the progress of your research here?"

"Research progress? There is no research progress at all!" Grand Duke Rimel was filled with resentment.

Moving from Dragon Island to Nevis, his physical problems have not been solved, his salary has not increased, he cannot suck human blood or the blood of high-energy monsters, and his residence is too cramped——

Master Nordmark also wanted to ask, is there any research progress? Is there any research progress?

"You should give me a few people with high blood pressure, high blood lipids, and sclerosis of the arteries. Let me suck a few mouthfuls of blood, chew the blood vessels, and then talk to me about the progress of the research!"

"Well……"

Didn’t I tell you this a long time ago?

You can't kill people, you can't suck human blood... you can't, you can't, you can't!

Moreover, in this world, humans with high blood pressure, high blood lipids, and high levels of blood vessel calcification are basically rich and powerful people.

Don't say that people like this can't be caught casually. Even if they commit crimes and go to jail, their trials and sentences are in full view of the public. They can't just be caught and chewed on your veins!

"Didn't I tell you to start with animal experiments? If you raise some animals with vascular calcification, you can start research!"

"I can't raise it!"

The Grand Duke was particularly agitated. That's right, raising animals is such a smelly and annoying thing. He really doesn't need to take action. He only needs to give orders, and naturally there will be low-level spellcasters running around to do the work——

But he has to give orders! What animals to raise, how to raise them, what to feed and drink, what kind of treatment the animals need to have...

It’s all up to him to come up with ideas, all up to him to use his brain!

So far, there have been twenty litters of rabbits and twenty cages of rats, and none of the rats or rabbits have shown hyperlipidemia, let alone the deposition of fatty plaques in blood vessels and vascular calcification... …

There are just endless questions:

"Your Majesty the Grand Duke, the rabbits don't eat! They usually eat grass. Shouldn't we give them meat?"

"Your Majesty the Grand Duke, the rabbit has diarrhea! - Is there too much fat mixed in the grass?"

"Your Majesty the Grand Duke, should we change to a different kind of fat? These mice don't seem to like the smell of butter..."

"Your Majesty the Grand Duke, those rats are banging against the cage again... Although it is to make them move less and grow more meat, is the five-inch long and two-inch wide cage too small for them?"

"His Excellency the Grand Duke..."

Bastard Nordmark mage!

He only said "High nutrition, high fat feeding, eat more and move less, you should gain weight quickly", and didn't care about anything else!

Leave it all to him!

Throw it to him!

Throw it to him!

What do you think of him, the Grand Duke of Rimmer, the majestic Duke of Blood, a half-legend!

"Oh, I can't raise it..." Gretel sighed softly. Well, it seems like it won’t work without his intervention——

I thought I could be lazy, tsk.

Gretel calmed down and began to look through the animal feeding report (a collection of wrong questions) submitted by the Grand Duke. While watching, he tutted, tutted:

"I only chose mouse and rabbit..."

"Nonsense! Others are more troublesome!"

When the experimental animals were first determined, Grete said this:

"Mouse is easier to raise, but it does not have a gallbladder, and its fat metabolism may be different from humans, so it is not easy to develop hyperlipidemia;"

"Rabbits are also easier to raise, but they reproduce a little slower than mice and eat more feed;"

"Pigs... In fact, the eating habits and physiological characteristics of pigs are the most similar to humans, but the growth cycle of pigs is too long, and their breeding takes up space... It would be great if there were mini pigs..."

"If you don't care about the cost, you can actually use monkeys, just like we did in the Eagle Country... But monkeys are too troublesome, difficult to catch, and difficult to raise..."

In the end, the Grand Duke chose mice and rabbits to start with. Nothing else. These two animals occupy a small area and are easy to raise. Moreover, they are already available on Dragon Island, and it is also convenient to bring an airship——

Dragon Island is too far north, and no monkeys—except Warcraft—can survive, but driving dozens of pigs onto the airship?

Even if the Nature Priest helps to control it, the Grand Duke of the Vampire Clan can't stand that style of painting just thinking about it!

However, so far, neither the mouse nor the rabbit has achieved the desired results. Grand Duke Rimmer even felt that by arranging this topic for him, Gretel was displeased with the Vampires and was deliberately teasing him:

"You'd better give me someone! Give me someone, I'll have a taste and I'll give you the answer right away - are there really no suitable patients? No prisoners? No prisoners of war? Then I'll go to the Old Continent and catch them myself. One is enough!"

"No way!" Grete resisted. Well, the key is not to catch prisoners locally or where to catch patients, but rather not to just "catch one to try" for the convenience of doing research:

"In this way, if suitable patients come to see you, you can taste their blood. - As for raising animals, let me think about it, and then I will probably give you a method..."

Troublesome, what are the causes of hyperlipidemia and vascular calcification? What are the high-risk factors? Based on these causes and high-risk factors, what experimental methods can be tried?

In addition to high-fat diet, what other medications can intervene?

What other surgical methods can intervene?

Which drugs are currently available? You don’t have to count on warfarin, you don’t have to count on vitamin D3… you don’t have to count on gene knockout, you don’t even have to count on it…

Ah, when will there be enough gene knockout mice to do whatever experiments you want to do...

Grete stayed in seclusion for three full days, going back and forth about the contents in the textbook related to hyperlipidemia, atherosclerosis, calcification, etc., especially those related to physiology, pathophysiology, biochemistry, and molecular biology. look.

I took a lot of notes, speculated on more than a dozen methods, and crossed out seven or eight methods. The notebook was a mess. On the fourth day, he finally felt confident and sat down in front of the Grand Duke:

"Don't say I don't care about you! Then, try these methods -"

Grand Duke Rimmer picked up the manuscript and took a look at it, and the corner of his mouth twitched. After reading it all from beginning to end, I sighed sincerely:

"They say you are a kind-hearted healer, but you are so cruel, even more cruel than our vampires!"

Gretel: "..."

Is this a thing?

Ah, is this a thing?

We torture these experimental animals all in order to find suitable treatments without causing human suffering!

My charity is aimed at humans. As for animals, well, I can only say that they are not humans...

Grand Duke Rimmer held the manuscript and went to work, struggling. He slapped the plan given by Gretel in front of his spell caster, which immediately caused a burst of exclamation:

"Remove part of the kidney? How much? At least one? - Your Excellency the Grand Duke, are you sure that if one kidney is removed, the rat can still live?"

"I don't care whether I can live or not." Grand Duke Rimmer rolled his eyes:

"Anyway, this is the experimental plan given by your great Nordmark Archmage. Cut one kidney, then cut the remaining one into quarters, one-third, half, three-quarters... …”

"As long as you can't cut it to death, cut it to death!"

Under the Grand Duke, a necromancer jumped up:

"I'll do this project! Give me fifty rats! Make sure you cut it quickly and well, and you won't kill a rat because of slippery hands!"

Entire project team: →_→

Is he really worthy of being a necromancer? I get excited when I hear a knife being used, and I get excited when I hear cutting up living things. Cutting off a bunch of organs and still not dying is simply the highest challenge...

"Okay, the kidney failure team is yours." The Grand Duke calmly threw out one item, and then looked at the second one:

"The next group is the tobacco extract group. Take the tobacco extract and try feeding, gavage, intramuscular injection, intravenous injection, and high-fat diet to observe the situation. Who will do it?"

"This...tobacco extract is so harmful..."

In the conference room, two therapists quietly put out their pipes. Finally, a natural priest was reluctantly pushed out:

"What, do I have to give birth to tobacco myself? The project team didn't even give me the budget to buy tobacco?!"

"The next group is the calcium chloride induction group. The test animals are given a large amount of calcium chloride, fed, intramuscular injection, intravenous injection...

Of course, you can also cut open the stomach, expose the aorta, and soak it with calcium chloride solution..."

"Then can we actively damage the blood vessels of experimental animals? Use vines to rub the inner wall of the blood vessels, or the outer walls of the blood vessels, to make them more likely to calcify?"

"Can you use electricity, fire, or freezing to damage blood vessels and make them prone to calcification?"

"How do you feel? There are more and more experiments to be done!"

Thanks to x-on:Red Comet Mars for the reward of 500 starting coins

The last four hours!

The last four hours!

There are still 433 votes left to reach 4,000, so please try harder!

If the 4,000 votes are not received during the double period, the cat will cry to the ground!

Asking for a monthly ticket! ! !

ps:

Reference papers for this chapter:

"Research Progress on Experimental Animal Models and Methods of Atherosclerosis"

"Study on arterial calcification in mice fed LDLR with high sugar and high fat"

"Research Progress in Animal Models of Vascular Calcification"

The cat is so tired after watching it, he wants a monthly ticket to comfort him...